In the Atherosclerosis Risk in Communities cohort, people with carotid atherosclerosis in mid-life were more likely to have worse hearing decades later. (JAMA Otolaryngology-Head & Neck Surgery)
Higher HDL cholesterol corresponded with a higher risk of fractures in individuals over age 70. (JAMA Cardiology)
Regarding screening children for lipid disorders, the U.S. Preventive Services Task Force plans to stick to its “I statement” (i.e., limited evidence precludes assessment of benefit-risk profile), the task force said in a draft recommendation statement.
Beware an increased risk of angioedema among real-world sacubitril/valsartan (Entresto) users recently switching from an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker. (Journal of the American College of Cardiology)
A 6-month exercise intervention conferred a reduction in atrial fibrillation symptom severity that lasted through 12 months, the ACTIVE-AF randomized trial showed. (JACC: Clinical Electrophysiology)
Physical activity also emerged as perhaps the first identified modifiable risk factor of cardiac conduction disease. (European Heart Journal)
Implantable cardioverter-defibrillator leads more than 10 years old don’t necessarily cause more complications during extraction — in the hands of experienced and skilled operators, that is. (Europace)
People are increasingly undergoing percutaneous coronary intervention at low-volume centers, a trend that may be affecting certain socioeconomic groups more than others. (PLOS One)
Voluntary reports suggest that MitraClip locking failures are increasing in incidence. Operators are advised to double-check the locking mechanism during device preparation and before final release in every case. (JACC: Cardiovascular Interventions)
Among anti-HER2 therapies for cancer, trastuzumab (Herceptin) and combination pertuzumab (Perjeta)/trastuzumab emtansine (Kadcyla) were associated with disproportionately more heart failure reports in a pharmacovigilance database. (JACC: CardioOncology)
The REGARDS algorithm emerged the winner in a showdown of stroke risk calculators. However, researchers report a need for continued refinement of modeling techniques. (JAMA)
In Florida, hospitals that self-attested themselves meeting Comprehensive Stroke Center criteria have shown lower stroke care quality compared with certified hospitals. (Stroke)
Stroke expert Ralph Sacco, MD, MS, former president of both the American Heart Association and the American Academy of Neurology, died last week at age 65. (Neurology)
Proposed as an early marker of cardiotoxicity from anthracycline therapy: the neutrophil-to-lymphocyte ratio. (Clinical Cardiology)
Fewer meals per day, not intermittent fasting, was associated with weight loss. (Journal of the American Heart Association)
Use of secondary prevention therapies for people with atherosclerotic cardiovascular disease continues to be subject to gender and racial disparities. (JAMA Network Open)
The BBC published a note apologizing for allowing a guest cardiologist to claim, unchallenged, excess cardiovascular deaths from COVID mRNA vaccines during a television segment.
Source: MedicalNewsToday.com
