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Public Interest in CPR; Local Antibiotics for Device Infections; Rehab for the Frail

Myocarditis associated with mRNA COVID-19 vaccines may be related to circulating free spike antigen, according to a study of antibody profiling and T-cell responses to immunization. (Circulation)

Buffalo Bills safety Damar Hamlin’s cardiac arrest last week prompted increased interest in online CPR education and resources, the American Heart Association said.

Both hypotension and hypertension were linked to mortality after out-of-hospital cardiac arrest. (Critical Care)

Pfizer was unable to get the U.S. Supreme Court on its side to offer “middle-income” Medicare patients financial assistance for its pricey drug tafamidis (Vyndaqel, Vyndamax). (Reuters)

A Mendelian randomization study suggested that sleep apnea and snoring cause hypertension and heart disease, not the other way around. (European Journal of Preventive Cardiology)

Thousands of deaths in Australia could be prevented each year if manufacturers complied with World Health Organization sodium benchmarks for packaged foods sold on the continent. (Hypertension)

The FDA cleared the Lightning Flash mechanical thrombectomy system for venous and pulmonary clots, Penumbra said.

People with atrial fibrillation may not expect the same outcomes from stroke thrombectomy, perhaps owing to their older age and greater comorbidity burden. (JAMA Network Open)

The burden of atrial fibrillation/atrial flutter varies around the world and is increasing in lower-income countries. (EP Europace)

For localized implantable cardiac device pocket infections, surgery to apply ultra-high-dose antibiotics directly to the infected site appeared to be a good alternative to device extraction. (Journal of the American College of Cardiology)

The R-One robot showed promise for percutaneous coronary intervention on simple lesions. (EuroIntervention)

The last two decades have seen improvements in lipid levels and modest increases in statin use in the U.S. (Journal of the American Heart Association)

Over 4 years of inclisiran (Leqvio) treatment, patients with high cardiovascular risk saw sustained reductions in LDL cholesterol and PCSK9 in the ORION-3 open-label extension study. One in 10 had increases in liver enzymes. (The Lancet Diabetes & Endocrinology)

The team behind the landmark cardiac xenotransplant case discussed the intraoperative management of the patient in the Annals of Thoracic Surgery.

Patients with acute decompensated heart failure derived greater benefits from physical rehabilitation if they were frail at baseline, a secondary analysis of REHAB-HF found. (JAMA Cardiology)

Based on x-rays of people diagnosed with acute pulmonary embolism, researchers suggested imaging markers for pre-existing chronic thromboembolic pulmonary hypertension. (CHEST)

The American Society of Echocardiography updated its rheumatic heart disease (RHD) guideline that covers all cardiac abnormalities caused by RHD, going beyond valvular stenosis and valvular regurgitation. (Journal of the American Society of Echocardiography)

  • Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow

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Source: MedicalNewsToday.com