In super-agers — people 80 and older with exceptional episodic memory — entorhinal cortex neurons were significantly larger compared with cognitively average peers and individuals 20-30 years younger. (Journal of Neuroscience)
A multimodal pain management protocol reduced postoperative opioids in arthroscopic knee or shoulder surgery patients, a randomized trial showed. (JAMA)
The NIH’s National Institute on Aging issued a statement on the Eisai and Biogen announcement that lecanemab reduced cognitive decline in a phase III trial of early Alzheimer’s disease.
Dimethyl fumarate (Tecfidera) led to a greater proportion of pediatric-onset MS patients with no new or newly enlarging T2 lesions than interferon beta-1a (Avonex), the CONNECT trial showed. (JAMA Network Open)
Asian, Black, and Hispanic individuals with mild cognitive impairment or dementia had lower odds of positive amyloid PET scans than white individuals, the IDEAS cohort showed. (JAMA Neurology)
Acromegaly was associated with a higher risk of Parkinson’s disease, Alzheimer’s disease, and all-cause dementia. (Neurology)
The National Football League (NFL) and NFL Players Association agreed to parameters of updated concussion protocols to rule out players who show gross motor instability like Miami Dolphins quarterback Tua Tagovailoa.
More research showed that antidepressant use during pregnancy did not increase the risk of neurodevelopmental disorders in children. (JAMA Internal Medicine)
A Canadian researcher proposed a mechanistic model for Alzheimer’s as a chronic autoimmune condition that attacks the brain. (Alzheimer’s & Dementia)
How can confidential patient information and care be balanced in people with preclinical Alzheimer’s disease? (Neurology)
Source: MedicalNewsToday.com
