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Distressing Dreams and Dementia; Global COVID-Brain Study; Biogen Resolves Claims

Distressing dreams predicted cognitive decline and all-cause dementia in middle-aged and older adults without cognitive impairment or Parkinson’s disease, especially men. (eClinicalMedicine)

A life expectancy model predicted mortality in people with dementia. (JAMA Internal Medicine)

What’s known about the long-term effects of COVID on the brain? Researchers for a global consortium assessed the data so far and reviewed plans for future research. (Alzheimer’s & Dementia)

Patient-centered care measures varied significantly by race and ethnicity among people with Alzheimer’s and dementia enrolled in Medicare Shared Savings Program Accountable Care Organizations. (JAMA Network Open)

Biogen agreed to pay $900 million to resolve allegations it contributed to false Medicare and Medicaid claims by paying kickbacks to induce physicians to prescribe the MS drugs interferon beta-1a (Avonex), natalizumab (Tysabri), and dimethyl fumarate (Tecfidera), the Department of Justice announced.

Conscious sedation was not superior to general anesthesia for endovascular treatment of acute posterior circulation stroke, an exploratory trial showed. (JAMA Neurology)

A smart gait tracker using radio waves effectively monitored disease severity, progression, and medication response of Parkinson’s patients at home. (Science Translational Medicine)

White matter microstructure and brain volume were altered in children exposed to air pollution. (Environmental Pollution)

Midlife serum metabolites made a modest contribution to dementia prediction after age was factored in. (BMC Medicine)

A study of monozygotic twins suggested memory and language decline in early Alzheimer’s is partly determined by the same genetic factors that influence amyloid-beta and tau. (Alzheimer’s & Dementia)

Atrophy and neurofilament light may be the best endpoints in prevention trial simulations of familial frontotemporal dementia; clinical measures could be potential endpoints for early symptomatic trials. (Nature Medicine)

  • Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more. Follow

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Source: MedicalNewsToday.com