Hearts in Extreme Heat; Pandemic’s Heart Transplant Policies; Entresto Titration

Preexisting atrial fibrillation was a predictor of poor outcomes after noncardiac surgery. (Journal of the American College of Cardiology)

Cardiovascular deaths tend to go up on extreme heat days exceeding 90°F in the U.S. (Circulation)

Statin users tended to have slower progression of arterial stiffness in Chinese adults at high atherosclerotic risk. (JAMA Network Open)

Could statins really be associated with a greater risk of cataracts? (Journal of the American Heart Association)

Outside high-income countries, more sedentary time still translates to greater risk of cardiovascular disease. (JAMA Cardiology)

Surveys reveal wide variation in attitudes and policies for heart transplantation during the COVID-19 pandemic. (Journal of Cardiac Failure)

Cytokinetics says the FDA is asking for more data on omecamtiv mecarbil before it can make a decision on approval for this selective cardiac myosin activator.

Right ventricular dysfunction on echocardiography can be telling of a heart failure patient’s ability to tolerate the maximum dose of sacubitril/valsartan (Entresto), an Italian study found. (ESC Heart Failure)

In people with hereditary transthyretin amyloidosis and polyneuropathy, eplontersen cut serum transthyretin and helped with neuropathy symptoms in the NEURO-TTRansform trial, AstraZeneca announced.

A Cleveland Clinic group reports that a minimalist approach can be applied to valve-in-valve transcatheter mitral valve replacement, too. (JACC: Cardiovascular Interventions)

Meta-analysis confirms a coronary artery calcium score of zero to have high negative predictive value for ruling out obstructive heart disease in people presenting with chest pain. (JACC: Cardiovascular Imaging)

The benefit of ticagrelor (Brilinta) and aspirin for secondary prevention dropped off after the first week of therapy among carriers of CYP2C19 loss-of-function alleles who had minor strokes, according to a secondary analysis of CHANCE-2. (JAMA Neurology)

Clinicians attest to disrupted cardiology services in Tigray, Northern Ethiopia, due to the ongoing war. (European Heart Journal)

Across several developing countries, the switch from biomass cooking fuel to propane did not help pregnant women lower their gestational blood pressure. (Hypertension)

A computer program may help track which rehab exercises best help stroke survivors regain use in their arms and hands. (PLOS Digital Health)