Neuroinflammation, microhemorrhages, brain hypoxia, and neuropathology were seen in SARS-CoV-2-infected non-human primates, including animals that did not develop severe respiratory disease. (Nature Communications)
A novel measure of delirium severity was associated with length of hospital stay and hospital costs. (JAMA Network Open)
Loss of subcortical wake-promoting neurons in Alzheimer’s disease may make patients drowsy. (JAMA Neurology)
The prevalence of short and long sleep duration was persistently higher among Black Americans versus those of other races and ethnicities from 2004 to 2018. (JAMA Network Open)
A single memory may be stored across multiple connected brain regions. (Nature Communications)
The estimated global prevalence of active headache disorder was 52%; the global prevalence of migraine was 14%. (Journal of Headache and Pain)
An interim analysis of the CONSONANCE study suggested that ocrelizumab (Ocrevus) showed benefits for both disability progression and cognitive decline in progressive multiple sclerosis, drug maker Genentech said.
Genes suggestive of new genetically associated processes in Alzheimer’s disease and related dementia, including the tumor necrosis factor alpha pathway, were identified in a massive genome-wide association study. (Nature Genetics)
Daily corticosteroids as initial treatment for boys with Duchenne muscular dystrophy led to better outcomes than an intermittent prednisone regimen in a randomized clinical trial. (JAMA)
The HOBSCOTCH program improved quality of life and subjective cognition in epilepsy patients at 3 months, but not at 6 months. (Neurology)
Brain charts based on more than 120,000 MRI scans showed how the human brain expands and shrinks over time. (Nature)
Source: MedicalNewsToday.com
