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Heavy Periods Seen in Obesity; T1D Tied to Fracture Risk

Women with obesity may have a higher risk of heavier periods due to delayed endometrial repair. “Although it is difficult to make strong recommendations based on this study alone, a common-sense approach would be to offer weight-loss support to women with a high BMI experiencing heavy periods,” suggested lead author Jacqueline Maybin, MBChB, PhD, of the University of Edinburgh, in a statement. (Journal of Endocrinology)

A new subgroup analysis of the phase III SONICS trial found that levoketoconazole (Recorlev) was effective at normalizing mean 24-h urinary free cortisol in people with Cushing’s and improved glycemic control in those with comorbid diabetes. (Frontiers in Endocrinology)

Almost a third of people with coronary artery disease also have diabetes — three times the diabetes prevalence as in the general population. (European Journal of Preventive Cardiology)

Following long-term denosumab (Prolia, Xgeva) treatment with zoledronate (Reclast) within 9 months wasn’t fully protective against bone loss or increase bone turnover in the initial 12 months. (Journal of Bone and Mineral Research)

Rates of obesity — and ironically also malnutrition — are simultaneously rising across the globe. (The Hill)

A small study found that people with type 1 diabetes had a significantly higher rate of fractures. “It is important to investigate what leads to an increased risk of fractures in type 1 diabetes. Our results suggest that in addition to bone features, balance and muscle strength also play a role,” said lead author Tatiane Vilaca, MD, PhD, of the University of Sheffield in England. (Journal of Bone and Mineral Research)

The U.K. Parliament’s Women and Equalities Committee is urging the government to not use body mass index in its strategy to tackle lockdown-exacerbated obesity, instead calling for a “health at every size” approach. (The Guardian)

Blood samples paired with machine learning was a useful tool for pinpointing osteoporosis. (Journal of Orthopaedic Surgery and Research)

  • Kristen Monaco is a staff writer, focusing on endocrinology, psychiatry, and dermatology news. Based out of the New York City office, she’s worked at the company for nearly five years.

Source: MedicalNewsToday.com