After its investigational adjunctive schizophrenia treatment CTP-692 (D-serine) flopped in a phase II study, Concert Pharmaceuticals said it’s throwing in the towel.
In 2019, about one-third of fatal heroin and fentanyl overdoses in Philadelphia also involved the animal tranquilizer xylazine. During 2010-2015, the agent was only detected in 2% of such overdoses. (Injury Prevention)
By switching its 2020 annual meeting from in-person to virtual, the American Psychiatric Association slashed its carbon footprint by an amount equivalent to burning 500 acres of dense forest or 11,000 tons of coal. (JAMA Network Open)
The Biden White House slammed the brakes on new rules expanding physicians’ ability to prescribe the opioid addiction drug buprenorphine, citing procedural missteps in the Trump administration’s rush to approve it. (The Philadelphia Inquirer)
Poor sleep was linked to increased risk for both frailty and depressive symptoms in older folks. (Journal of the American Geriatrics Society)
For adults over 50, THC-based medicines increased the rate of dizziness and perception disorder, but this wasn’t seen with cannabinoid-only based medicines. (JAMA Network Open)
Psychiatrist and Hasidic rabbi Abraham J. Twerski, MD, best known for his work in treating substance abuse, died at the age of 90 from COVID-19. (ABC News)
Especially for women with less social support, COVID-19 pandemic lockdowns magnified symptoms of anxiety and depression for pregnant women. (Acta Obstetricia et Gynecologica Scandinavica)