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Drug OK’d for Genetic Obesity; COVID-19 & Diabetic Retinopathy

The FDA approved the melanocortin 4 receptor (MC4R) agonist setmelanotide (Imcivree) for chronic weight management in patients 6 and older with obesity due to confirmed POMC, PCSK1 or LEPR deficiency, Rhythm Pharmaceuticals announced.

Is it cost-effective for older men with a history of falling to get a DXA scan? A new study says yes. (JAMA Network Open)

COVID-19 patients with diabetic retinopathy may face up to a five-fold increased risk of needing intubation in the hospital. “There is increasing evidence that there is significant damage to the blood vessels in the lung and other organs in patients hospitalized with severe COVID-19. People with diabetes are at high risk of vascular complications affecting the large and small blood vessels,” said senior study author Janaka Karalliedde, MBBS, PhD, of King’s College London, in a statement. (Diabetes Research and Clinical Practice)

Rates of heart failure hospitalizations in the U.S. have declined since 1995, but the trend has been substantially weaker for diabetic patients, according to a JAMA Cardiology research letter.

Among New York City patients diagnosed with COVID-19 in March, pre-existing hypothyroidism and receipt of thyroid hormone therapy had no bearing on risk of hospitalization, mechanical ventilation, or mortality — suggesting “no additional precautions or consultations are needed” for those with hypothyroidism. (Frontiers in Endocrinology)

Although male athletes who abused androgen steroids typically saw an immediate fertility decline, it tended to bounce back almost to normal after stopping the anabolic agents. (The Journal of Clinical Endocrinology & Metabolism)

ICD-10 diagnostic codes plus demographic data flagged potentially transgender individuals in electronic health records. “Our findings reveal that this two-step question technique can help us recognize those whose gender identity does not match their sex assigned at birth, whether or not they label themselves transgender,” said lead study author Samuel Dubin, MD, of NYU Langone Health, in a statement. (Transgender Health)

Singer Meghan Trainor recently opened up about her gestational diabetes diagnosis. (Today)

  • Kristen Monaco is a staff writer, focusing on endocrinology, psychiatry, and dermatology news. Based out of the New York City office, she’s worked at the company for nearly five years.

Source: MedicalNewsToday.com