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MIS-C in Young Adults; ACE2 Insights; Generic Vascepa

The Kawasaki disease-like multisystem inflammatory syndrome in children tied to COVID-19 is also being seen in young adults, the Washington Post reports.

Kids have less ACE2 gene expression in the nasal epithelium (the route of entry into cells for the COVID-19 virus at the main point of entry into the body) than do adults, according to a study that may help explain children’s lower risk overall. (JAMA)

ACE inhibitors and angiotensin receptor blockers didn’t raise ACE2 levels in serum, according to a study on the preprint server medRxiv.

Blanket do-not-resuscitate orders for COVID-19 patients may be inappropriate, given the lack of good U.S. survival data, a group argued in Circulation: Cardiovascular Quality and Outcomes.

The first generic version of icosapent ethyl (Vascepa) was approved by the FDA, although product launch is likely to be delayed amid its patent battle. (Endpoints News)

Imaging-proven ischemic stroke occurred in only 0.9% of COVID-19 cases in one New York City healthcare system but those cases were more severe, linked to higher D-dimer levels, and had higher mortality rates than in other patients. (Stroke)

The stroke rate in COVID-19 patients seen at three Italian centers was higher. (Radiology)

Novel P2Y12 receptor antagonist selatogrel yielded “profound, rapid” antiplatelet activity in a single dose among acute myocardial infarction patients in a small dose-finding trial. (Journal of the American College of Cardiology)

New billing codes may set the stage for expanding 3D printing in cardiology, Cardiovascular Business reports.

Mechanical thrombectomy volume dropped 21% while imaging delays in ischemic stroke rose by nearly 30 minutes during the coronavirus pandemic in France; lytic use and thrombectomy also dropped by 25% across more than 200 centers in China. (Stroke)

FDA gave emergency use authorization to G Medical Innovations’s Vital Signs Monitoring System electrocardiogram patch for remote QT interval monitoring of COVID-19 patients. (MassDevice)

Blood flow recovers before brain function around microinfarcts, researchers reported in Science Advances.

Spirituality was linked to better quality of life among stroke survivors and their caregivers in a study in Circulation: Cardiovascular Quality and Outcomes.

European regulators cleared Edwards Lifesciences’s Pascal transcatheter valve repair system for tricuspid regurgitation. (MassDevice)

Cardiovascular primary prevention for women takes a somewhat different approach than for men, as a review in the Journal of the American College of Cardiology detailed.

Last Updated May 26, 2020

Source: MedicalNewsToday.com