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Light and sound that induced gamma waves reduced large swaths of amyloid plaques in mice and improved cognitive and memory symptoms similar to those found in Alzheimer’s patients. (Cell)
Flavonoid-rich cocoa curbed fatigue in relapsing-remitting multiple sclerosis patients. (Journal of Neurology, Neurosurgery & Psychiatry)
Can pathogens trigger Alzheimer’s? Scientific American explores theories.
Manganese accelerated cell-to-cell exosomal transmission of alpha-synuclein, which may explain links between chronic exposure to the metal and Parkinson’s. (Science Signaling)
Exposure to silica was tied to amyotrophic lateral sclerosis (ALS) risk in Europe. (Journal of Neurology, Neurosurgery & Psychiatry)
Nilotinib (Tasigna), a leukemia treatment, reduced toxic alpha-synuclein levels in a phase II study of people with Parkinson’s disease. (FierceBiotech)
Seizure detection software correctly identified only 53% of seizures in ambulatory EEG files. (Neurology)
Allergan said its new drug application for ubrogepant, an oral CGRP receptor antagonist for acute migraine, was accepted at the FDA.
Bryostatin-1, a protein kinase (PKC)-epsilon modulator originally developed as a cancer drug, is being tested in a phase II study of patients with moderate to severe Alzheimer’s disease, drugmaker Neurotrope reported.
Should neurologists worry about climate change? (The Lancet Neurology)