Morning Break: More Guns, More Kid Deaths; Culture Change; FDA’s 2018 Record

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Researchers linked handgun ownership to an increase in child deaths. (CNN Health, Pediatrics)

The FDA boasted that 2018 was a “record year for device innovation” with 106 novel products approved, up from 25 in 2009.

Ibrutinib (Imbruvica) plus obinutuzumab (Gazyva) won approval for first-line use in chronic lymphocytic leukemia or small lymphocytic lymphoma, Janssen announced.

Takeda’s dengue vaccine met its endpoints in a pivotal trial, but the company didn’t say how it performed in people not previously exposed to the virus. (Reuters)

Nobel laureate Craig Mello, PhD, gets caught up in the gene-edited babies controversy in China. (NBC News)

Medicine needs a change in culture in order to keep its best doctors, Marschall Runge, MD, writes in STAT.

Alexion said its ravulizumab (Ultomiris) met the primary endpoint in a trial in atypical hemolytic uremic syndrome. The C5 complement inhibitor was first approved last month for paroxysmal nocturnal hemoglobinuria.

Plaintiffs in a federal lawsuit against Monsanto/Bayer, alleging that the herbicide glyphosate (Roundup) causes cancer, can introduce evidence that the company tried to ghostwrite scientific papers and influence researchers’ findings, the presiding judge ruled. (Reuters)

A data breach leads to HIV status information being exposed for an estimated 14,000 foreign visitors and locals in Singapore. (Gizmodo)

HIV cases increased by 4% in Connecticut in 2017. (WTNH)

Apple and Aetna are developing an Apple Watch app that provides monetary rewards to users achieving healthy-lifestyle goals. (CNBC)

Patients who received aggressive high blood pressure treatment were less likely to have minor memory and thinking challenges than those receiving standard blood pressure treatment. (New York Times)

Survival outcomes in head and neck cancer were significantly for patients taking NSAIDs such as ibuprofen and aspirin. (TimesNowNews.com)

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