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Alzheimer’s Vaccine; ASA + NAC for Bipolar Depression; Neuroscience Pioneer Dies

An investigational Alzheimer’s vaccine boosted anti-beta amyloid antibody titers in a small phase IIa trial, developer United Neuroscience announced.

In similar news, a protein currently being developed as an ischemic stroke treatment — 3K3A-activated protein C — showed promise as an early-stage Alzheimer’s treatment. (Journal of Experimental Medicine)

Eisai and Purdue Pharma applied for marketing approval for their insomnia drug lemborexant, a follow-on to the orexin receptor antagonist suvorexant (Belsomra).

Aspirin plus the antioxidant N-acetylcysteine helped to ease depressive symptoms in people with bipolar depression. (The Journal of Clinical Psychiatry)

Pregnant women with deployed military spouses may face a higher risk for perinatal depression. (Royal Army Medical Corps)

Vitamin B supplements — B12, B6, and folic acid — may help to support attention and vigilance in schizophrenia related first-episode psychosis, although the benefits appeared to stop there. “Although they are not improving a patient’s concentration skills, they may be protecting these skills from declining,” said a study co-author in a press release. (Biological Psychiatry)

Although not recognized by the DSM-5, a new study looked at how “addiction” to Facebook can impact overall health and behavior. (Journal of Behavioral Addictions/MedPage Today)

Former NIMH director and neuroscience pioneer Lewis L. Judd, MD, died last month at the age of 88. Judd chaired the University of California San Diego’s psychiatry department for decades. (New York Times)