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Nation’s Deadliest Drug; Severe Autism Exclusions; Stem Cells for MS

Fentanyl was linked to 29% of all overdose deaths in 2016, surpassing heroin as the drug most often involved in fatal overdoses, according to the CDC. (National Vital Statistics Report)

Children with severe autism may be excluded or underrepresented in recent treatment studies. (Journal of Autism and Developmental Disorders)

Miami doctors who first tested the Havana embassy workers who had experienced unusual noises or pressure sensations said the diplomats had a vestibular and cognitive pathology different from concussion symptoms. (Laryngoscope Investigative Otolaryngology)

BrainStorm Cell Therapeutics received approval to study stem cell treatment in progressive multiple sclerosis patients. (Reuters)

Daily oral buprenorphine-naloxone was more cost-effective than monthly injections of extended-release naltrexone for opioid use disorder. (Annals of Internal Medicine)

Even so, Indivior plans to launch a cheaper version of its buprenorphine-naloxone treatment (Suboxone) to keep copycats at bay. (Reuters)

You can perhaps thank Neanderthal genes for the shape of your skull. (CNN)

Depressed children had a fivefold risk of concussion when playing football than children without a depression diagnosis. (Journal of Pediatrics)

Researchers produced a detailed map of the brain’s genetic landscape — complete with gene regulators, cellular data, and human developmental information. (New York Times)

Eli Lilly paid AC Immune $80.5 million upfront for a preclinical Alzheimer’s drug. (Reuters)

Preliminary guidance from Britain’s National Institute for Health and Care Excellence (NICE) nixes both inotersen (Tegsedi) and patisiran (Onpattro) for patients with hereditary transthyretin-mediated amyloidosis, as too expensive for the drugs’ modest clinical benefits. (FiercePharma)

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Source: MedicalNewsToday.com